Globally, about 39% fewer people acquired HIV in 2023 compared with 2010, with sub-Saharan Africa achieving the steepest reduction (-56%). Nonetheless, an estimated 1.3 million people acquired HIV in 2023—over three times more than the target of 370,000 or fewer new infections in 2025.Â
Three regions are experiencing rising numbers of new HIV infections: eastern Europe and Central Asia, Latin America, and the Middle East and North Africa.Â
For the first time in the history of the HIV pandemic, more new infections are occurring outside sub-Saharan Africa than in sub-Saharan Africa. This reflects both the prevention achievements in much of sub-Saharan Africa and the lack of comparable progress in the rest of the world, where people from key populations and their sex partners continue to be neglected in most HIV programs.
